The potential application of ribozymes for the treatment of hematological disorders

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The potential application of ribozymes for the treatment of hematological disorders.

With the identification and increasing understanding of the genes involved in neoplastic transformation has come the realization that abrogation of these genes' products may lead to cell death or a return to normalcy. The use of ribozymes and their nucleic acid cousins, antisense oligodeoxynucleotides (ODNs), are two such ways of perturbing the disease-related gene expression. This review will ...

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ژورنال

عنوان ژورنال: Journal of Leukocyte Biology

سال: 1999

ISSN: 0741-5400

DOI: 10.1002/jlb.66.3.361